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      FACULTY OF HEALTH SCIENCES

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      HEM 207 | Course Introduction and Application Information

      Course Name
      Fundamentals of Health III
      Code
      Semester
      Theory
      (hour/week)
      Application/Lab
      (hour/week)
      Local Credits
      ECTS
      HEM 207
      Fall
      6
      0
      6
      7

      Prerequisites
      None
      Course Language
      Turkish
      Course Type
      Required
      Course Level
      First Cycle
      Mode of Delivery face to face
      Teaching Methods and Techniques of the Course Lecture / Presentation
      National Occupation Classification -
      Course Coordinator
      • Öğr. Gör. Dr. Ebru Dığrak
      Course Lecturer(s)
      • Dr. Öğr. Üyesi Elif BARIŞ
      • Dr. Öğr. Üyesi Özge ERTENER
      • Öğr. Gör. Dr. Ebru Dığrak
      • Öğr. Gör. Dr. Kazım Kıratlı
      Assistant(s) -
      Course Objectives At the end of the course; students are expected to recognize the etiopathogenesis of diseases, the basic morphologic changes that occur during diseases, acquire basic knowledge and skills necessary for selection and use of medicines indicated for the treatment of diseases and learn the human infections and their mechanisms of formation, prevention and treatment.
      Learning Outcomes

      The students who succeeded in this course;

      • List infectious diseases in humans.
      • Explain the transmission mechanisms of infectious diseases, prevention and treatment approaches from infectious diseases.
      • Recognize the basic concepts of pharmacology.
      • Define the routes of administration of drugs, the stages of absorption, distribution, metabolism and elimination after they entered the body and the practical importance of these concepts.
      • Define drug action mechanisms, the impact of dose in terms of drug effectiveness, adverse and toxic effects of drugs as well as the drug interactions
      • Identify the mechanisms of cell injury, adaptation, tissue repair and wound healing.
      • Discuss the general features, types, systemic effects , morphological findings of inflammation, features, etiology, molecular basis and nomenclature of cancer.
      • Discuss the pathogenesis and morphological findings of hemodynamic disorders, thromboembolic diseases, infarction and shock.
      Course Description This course includes the topics in cellular responses to stress, cell injury and death, acute & chronic inflammation, tissue repair and wound healing, hemodynamic disorders, thromboembolic diseases, infarction, shock, neoplasia, pathology of infectious diseases, infectious diseases related to systems, host defense mechanisms, specific host infections, the effects of drugs on the body, the action mechanisms of drugs, the treatment approaches against adverse side effects and toxicity, the factors modifying the drug effect, and the personalization of the treatment.
      Related Sustainable Development Goals

       



      Course Category

      Core Courses
      X
      Major Area Courses
      Supportive Courses
      Media and Management Skills Courses
      Transferable Skill Courses

       

      WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

      Week Subjects Related Preparation
      1 -Introduction to pharmacology: Definition and basic concepts -Introduction to Pathology -Epidemiology of Infectious Diseases - S. Oğuz Kayaalp, " Akılcıl Tedavi Yönünden Tıbbi Farmakoloji", bölüm 1 Genel Farmakoloji, Farm Akokinetik Ve Toksikoloji, Cilt 1, Sayfa 3-9. 13. baskı (Pelikan Yayıncılık, 2012). - Yaman Örs, Patoloji ve Tıptaki Yeri, sayfa 1-2, Temel Patoloji, Mocan Kuzey G, Özdamar Ş.O, Zergeroğlu S. Güneş Kitabevi, 2007. - Selda Seçkin, Dünyada ve Ülkemizde Patolojinin Tarihçesi, sayfa:3-5, Temel Patoloji, Mocan Kuzey G, Özdamar Ş.O, Zergeroğlu S. Güneş Kitabevi, 2007. - Görak G, Savaşer S, Yıldız S. (2011). Bulaşıcı Hastalıklar Hemşireliği, İstanbul Medikal Yayıncılık, 1. Baskı, İstanbul. ss: 62-67
      2 -Medicine administration routes -Cellular Responses to Stress: Basic Concepts, mechanisms of adaptation - Basic Approaches in Infectious Diseases - Whalen K, " Farmakoloji: Lippincott’ s illustrated reviews", bölüm 1 İlaç Tedavisinin Prensipleri Sayfa 1-22. 3. baskı (Nobel Tıp Kitabevi, 2009). -S. Oğuz Kayaalp, " Akılcıl Tedavi Yönünden Tıbbi Farmakoloji", bölüm 1 Genel Farmakoloji, Farm Akokinetik Ve Toksikoloji, Cilt 1, Sayfa 16-31. 13. baskı (Pelikan Yayıncılık, 2012). - Richard N.Mitchell, Hücre hasarı, hücre ölümü ve adaptasyonlar, Bölüm 1, sayfa: 1-5, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım, Nobel Tıp Kitabevleri, 2014. - Aydanur Kargı, Erdener Özer, Hücre zedelenmesi ve hücre ölümü, Kısım 1, sayfa 9-44, Temel Patoloji, Mocan Kuzey G, Özdamar Ş.O, Zergeroğlu S. Güneş Kitabevi, 2007 - Görak G, Savaşer S, Yıldız S. (2011). ss: 1-15
      3 -Pharmacokinetics -Causes and mechanisms of cell injury and cell death -Immunization and Prevention, Control in Infectious Diseases - Whalen K, " Farmakoloji: Lippincott’ s illustrated reviews", bölüm 1 İlaç Tedavisinin Prensipleri Sayfa 1-22. 3. baskı (Nobel Tıp Kitabevi, 2009). - S. Oğuz Kayaalp, " Akılcıl Tedavi Yönünden Tıbbi Farmakoloji", bölüm 1 Genel Farmakoloji, Farm Akokinetik Ve Toksikoloji, Cilt 1, Sayfa 10-64. 13. baskı (Pelikan Yayıncılık, 2012). - Richard N.Mitchell, Hücre hasarı, hücre ölümü ve adaptasyonlar, Bölüm 1, sayfa: 6- 28, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım, Nobel Tıp Kitabevleri, 2014. - Aydanur Kargı, Erdener Özer, Hücre zedelenmesi ve hücre ölümü, Kısım 1, sayfa 9-44, Temel Patoloji, Mocan Kuzey G, Özdamar Ş.O, Zergeroğlu S. Güneş Kitabevi, 2007. - Görak G, Savaşer S, Yıldız S. (2011). ss:70-94, 17-37.
      4 -Pharcodynamics -Morphology of cell injury and cell death -Surveillance and Notifiable Infectious Diseases - Health Care Related Infections - Whalen K, " Farmakoloji: Lippincott’ s illustrated reviews", bölüm 1 İlaç Tedavisinin Prensipleri Sayfa 23-36. 3. baskı (Nobel Tıp Kitabevi, 2009). - S. Oğuz Kayaalp, " Akılcıl Tedavi Yönünden Tıbbi Farmakoloji", bölüm 1 Genel Farmakoloji, Farm Akokinetik Ve Toksikoloji, Cilt 1, Sayfa 65-89. 13. baskı (Pelikan Yayıncılık, 2012). - Richard N.Mitchell, Hücre hasarı, hücre ölümü ve adaptasyonlar, Bölüm 1, sayfa: 6- 28, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım, Nobel Tıp Kitabevleri, 2014. - Aydanur Kargı, Erdener Özer, Hücre zedelenmesi ve hücre ölümü, Kısım 1, sayfa 9-44, Temel Patoloji, Mocan Kuzey G, Özdamar Ş.O, Zergeroğlu S. Güneş Kitabevi, 2007. - Görak G, Savaşer S, Yıldız S. (2011). ss:67-94
      5 -Factors that change the effects of drugs and drug interactions -Acute inflammation -Fever of Unknown Cause - Whalen K, " Farmakoloji: Lippincott’ s illustrated reviews", bölüm 1 İlaç Tedavisinin Prensipleri Sayfa 23-36. 3. baskı (Nobel Tıp Kitabevi, 2009). - S. Oğuz Kayaalp, " Akılcıl Tedavi Yönünden Tıbbi Farmakoloji", bölüm 1 Genel Farmakoloji, Farm Akokinetik ve Toksikoloji, Cilt 1, Sayfa 80-113. 13. baskı (Pelikan Yayıncılık, 2018). - Yavuz Özoran, Ümit Çobanoğlu, Akut ve Kronik inflamasyon, Kısım 2, sayfa:45-62, Temel Patoloji, Mocan Kuzey G, Özdamar Ş.O, Zergeroğlu S., Güneş Kitabevi, 2007. -Ayşe Willke Topçu, Güner Söyletir, Mehmet Doğanay (2008) , Enfeksiyon Hastalıkları ve Mikrobiyolojisi, Bölüm 5 Kısım 26, Ateş ve Nedeni Bilinmeyen Ateş, Sayfa 503-541
      6 -Medicines used in the treatment of pain and inflammation -Chronic inflammation -Respiratory Transmitted Infections - Whalen K, " Farmakoloji: Lippincott’ s illustrated reviews", bölüm 39 Antiinflamatuvar, Antipiretik ve Analjezik İlaçlar, Sayfa 508-526. 3. baskı (Nobel Tıp Kitabevi, 2009). - S. Oğuz Kayaalp, " Akılcıl Tedavi Yönünden Tıbbi Farmakoloji", bölüm 10 Otakoidler, Cilt 2, Sayfa 1327-1344. 13. baskı (Pelikan Yayıncılık, 2012). - Yavuz Özoran, Ümit Çobanoğlu, Akut ve Kronik inflamasyon, Kısım 2, sayfa:45-62, Temel Patoloji, Mocan Kuzey G, Özdamar Ş.O, Zergeroğlu S. Güneş Kitabevi, 2007. - Görak G, Savaşer S, Yıldız S. (2011). ss: 95-133.
      7 -Drugs used in the treatment of cardiovascular system diseases (1) -Tissue repair, Healing by first and second intention -Gastrointestinal System Infections and Hepatitis - Whalen K, " Farmakoloji: Lippincott’ s illustrated reviews", bölüm 16-19, Kardiyovasküler Sistemi Etkileyen İlaçlar, Sayfa 203-256. 3. baskı (Nobel Tıp Kitabevi, 2015). - S. Oğuz Kayaalp, " Akılcıl Tedavi Yönünden Tıbbi Farmakoloji", bölüm 3 Kalp-Damar Sîstemi İlaçlari, Cilt 1, Sayfa 379-476. 13. baskı (Pelikan Yayıncılık, 2012). - Sema Zergeroğlu, Doku tamiri, regenerasyon, iyileşme ve fibrozis, Kısım 3, sayfa:63-76, Temel Patoloji, Mocan Kuzey G, Özdamar Ş.O, Zergeroğlu S. Güneş Kitabevi, 2007. - Görak G, Savaşer S, Yıldız S. (2011). ss:135-170
      8 Midterm exam
      9 -Midterm Exam Evaluation -Drugs used in the treatment of cardiovascular system diseases (2) -Hemodynamic disorders (edema, hyperemia, congestion and hemorrhage) -Cardiovascular System and Central Nervous System Infections - Whalen K, " Farmakoloji: Lippincott’ s illustrated reviews", bölüm 16-19, Kardiyovasküler Sistemi Etkileyen İlaçlar, Sayfa 203-256. 3. baskı (Nobel Tıp Kitabevi, 2015). - S. Oğuz Kayaalp, " Akılcıl Tedavi Yönünden Tıbbi Farmakoloji", bölüm 3 Kalp-Damar Sîstemi İlaçlari, Cilt 1, Sayfa 379-476. 13. baskı (Pelikan Yayıncılık, 2012). - Şükrü Oğuz Özdamar, Hemodinamik Bozukluklar: Tromboembolizm ve Şok, Kısım 4, sayfa:77-92, Temel Patoloji, Mocan Kuzey G, Özdamar Ş.O, Zergeroğlu S. Güneş Kitabevi, 2007. - Ayşe Willke Topçu, Güner Söyletir, Mehmet Doğanay (2008) , Enfeksiyon Hastalıkları ve Mikrobiyolojisi, Bölüm 12, Kardiyovasküler Enfeksiyonlar, Sayfa 1003-1041 -Ayşe Willke Topçu, Güner Söyletir, Mehmet Doğanay (2008) , Enfeksiyon Hastalıkları ve Mikrobiyolojisi, Bölüm 17, Santral Sinir Sistemi Enfeksiyonları, Sayfa 1375-1487
      10 -Medicines used in the treatment of Respiratory System Diseases -Thromboembolic disease, infarctus and shock -Zoonoses - Whalen K, " Farmakoloji: Lippincott’ s illustrated reviews", bölüm 40 Solunum Sistemi Hastalıklarının tedavisinde kullanılan ilaçlar, Sayfa 527-539. 3. baskı (Nobel Tıp Kitabevi, 2009). - S. Oğuz Kayaalp, " Akılcıl Tedavi Yönünden Tıbbi Farmakoloji", bölüm 5; Solunum Sistemi ile ilg ili Bazı İlaçlar, Cilt 1, Sayfa 609-640. 13. baskı (Pelikan Yayıncılık, 2012). - Şükrü Oğuz Özdamar, Hemodinamik Bozukluklar: Tromboembolizm ve Şok, Kısım 4, sayfa:77-92, Temel Patoloji, Mocan Kuzey G, Özdamar Ş.O, Zergeroğlu S. Güneş Kitabevi, 2007. - Görak G, Savaşer S, Yıldız S. (2011). ss: 207-230
      11 -Infection and Antimicrobial Drugs (1) -Neoplasia 1 : Disorders of Cell growth and differantiation, etiopathogenesis of cancer and carcinogenesis -Diseases Transmitted by Vectors - Whalen K, " Farmakoloji: Lippincott’ s illustrated reviews", bölüm 28-29 Kemoterapötik ilaçlar, Sayfa 355-383. 3. baskı (Nobel Tıp Kitabevi, 2009). - S. Oğuz Kayaalp, " Akılcıl Tedavi Yönünden Tıbbi S. Oğuz Kayaalp, " Akılcıl Tedavi Yönünden Tıbbi Farmakoloji", bölüm 2 Antibiyotikler Ve Diğer Kem Oterapötikler, Cilt 1, Sayfa 225-282. 13. baskı (Pelikan Yayıncılık, 2012). - Alexander J. McAdam, Arlene H. Sharpe, Neoplazi, Bölüm 5, sayfa: 162-214, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım, Nobel Tıp Kitabevleri, 2014, ISBN: 978-605-335-002-6. - Canan Ersöz, Neoplazi, Kısım 7, sayfa:141-162, Temel Patoloji, Mocan Kuzey G, Özdamar Ş.O, Zergeroğlu S. Güneş Kitabevi, 2007. - Görak G, Savaşer S, Yıldız S. (2011). ss:231-265
      12 -Enfeksiyon ve Antimikrobiyal İlaçlar (2) -Neoplasia 2 : Nomenclature, characteristics of benign and malignant tumors, grading and staging of malignant tumors -Urinary System Infections -Sexually Transmitted Diseases and HIV Infection - Whalen K, " Farmakoloji: Lippincott’ s illustrated reviews", bölüm 28-29 Kemoterapötik ilaçlar, Sayfa 355-383. 3. baskı (Nobel Tıp Kitabevi, 2009). - S. Oğuz Kayaalp, " Akılcıl Tedavi Yönünden Tıbbi S. Oğuz Kayaalp, " Akılcıl Tedavi Yönünden Tıbbi Farmakoloji", bölüm 2 Antibiyotikler ve Diğer Kem Oterapötikler, Cilt 1, Sayfa 225-282. 13. baskı (Pelikan Yayıncılık, 2012). - Alexander J. McAdam, Arlene H. Sharpe, Neoplazi, Bölüm 5, sayfa: 162-214, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım, Nobel Tıp Kitabevleri, 2014. - Canan Ersöz, Neoplazi, Kısım 7, sayfa:141-162, Temel Patoloji, Mocan Kuzey G, Özdamar Ş.O, Zergeroğlu S. Güneş Kitabevi, 2007. - Görak G, Savaşer S, Yıldız S. (2011). ss:171-205
      13 -Drugs that are effective on the endocrine system -Neoplasia 3: Laboratory diagnosis of cancer and clinical models - Intestinal Parasitic Diseases and Protozoal Diseases - Whalen K, " Farmakoloji: Lippincott’ s illustrated reviews", bölüm 23-24 Endokrin Sistemi Etkileyen ilaçlar, Sayfa 301-325. 3. baskı (Nobel Tıp Kitabevi, 2009). - S. Oğuz Kayaalp, " Akılcıl Tedavi Yönünden Tıbbi Farmakoloji", bölüm 8 Endokrin Sistem Farmakolojisi, Cilt 2, Sayfa 1057-1118. 13. baskı (Pelikan Yayıncılık, 2012). - Alexander J. McAdam, Arlene H. Sharpe, Neoplazi, Bölüm 5, sayfa: 162-214, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım, Nobel Tıp Kitabevleri, 2014. - Canan Ersöz, Neoplazi, Kısım 7, sayfa:141-162, Temel Patoloji, Mocan Kuzey G, Özdamar Ş.O, Zergeroğlu S. Güneş Kitabevi, 2007. -Görak G, Savaşer S, Yıldız S. (2011). ss: 207-265
      14 -Drugs acting on the central nervous system -Neoplasia 4: Cancer with cases -Skin, Soft Tissue, Bone and Joint Infections -- Mpox Infections - Whalen K, " Farmakoloji: Lippincott’ s illustrated reviews", bölüm 23-24 Endokrin Sistemi Etkileyen ilaçlar, Sayfa 301-325. 3. baskı (Nobel Tıp Kitabevi, 2009 ). - S. Oğuz Kayaalp, " Akılcıl Tedavi Yönünden Tıbbi Farmakoloji", bölüm 8 Endokrin Sistem Farmakolojisi, Cilt 2, Sayfa 1057-1118. 13. baskı (Pelikan Yayıncılık, 2012). - Alexander J. McAdam, Arlene H. Sharpe, Neoplazi, Bölüm 5, sayfa: 162-214, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım, Nobel Tıp Kitabevleri, 2014. - Canan Ersöz, Neoplazi, Kısım 7, sayfa:141-162, Temel Patoloji, Mocan Kuzey G, Özdamar Ş.O, Zergeroğlu S. Güneş Kitabevi, 2007. -Görak G, Savaşer S, Yıldız S. (2011). ss:39-65
      15 Review Of The Course
      16 Final exam

       

      Course Notes/Textbooks
      1. Whalen K, " Farmakoloji: Lippincott’ s illustrated reviews", bölüm 1 İlaç Tedavisinin Prensipleri Sayfa 1-22. 3. baskı (Nobel Tıp Kitabevi, 2009), ISBN: 978-975-420-714-9
      2. S. Oğuz Kayaalp, " Akılcıl Tedavi Yönünden Tıbbi Farmakoloji", bölüm 1 Genel Farmakoloji, Farm Akokinetik Ve Toksikoloji, Cilt 1, Sayfa 10-64. 13. baskı (Pelikan Yayıncılık, 2012), ISBN: 605-52-70-10-2
      3. Kumar, Abbas, Aster, Robbins Temel Patoloji, Dokuzuncu Basım, 2014, Nobel Tıp Kitabevleri, ISBN: 978-605-335-002-6
      4. Gamze Mocan Kuzey, Şükrü Oğuz Özdamar, Sema Zergeroğlu, Temel Patoloji, 2007, Güneş Kitabevi, ISBN: 978-605-335-002-6
      5. Görak G, Savaşer S, Yıldız S. (2011). Bulaşıcı Hastalıklar Hemşireliği, İstanbul Medikal Yayıncılık, 1. Baskı, İstanbul. ISBN:978-9944-211-86-4
      6. Ayşe Willke Topçu, Güner Söyletir, Mehmet Doğanay (2008) , Enfeksiyon Hastalıkları ve Mikrobiyolojisi, 3. Baskı, Nobel Tıp Kitapevi, ISBN:978-975-420-634-0
      Suggested Readings/Materials

      ​

      1. Carie A. Braun, Cindy M. Anderson, Pathophysiology “A clinical approach”, second edition, 2011, Lippincott Williams & Wilkins, ISBN: 978-1-60547-304-8                
      2. Gary D. Hammer, Stephen J.McPhee, Pathophysiology of disease “An Introduction to Clinical medicine” seventh edition, 2014,  Lange,ISBN: 978-0-07-180600-8.
      3. Sağlık Bakanlığı COVID-19 Salgın Yönetimi ve Çalışma Rehberi https://covid19.saglik.gov.tr/TR-66393/covid-19-salgin-yonetimi-ve-calisma-rehberi.html

       

      EVALUATION SYSTEM

      Semester Activities Number Weigthing
      Participation
      Laboratory / Application
      Field Work
      Quizzes / Studio Critiques
      Portfolio
      Homework / Assignments
      1
      30
      Presentation / Jury
      Project
      Seminar / Workshop
      Oral Exams
      Midterm
      1
      30
      Final Exam
      1
      40
      Total

      Weighting of Semester Activities on the Final Grade
      2
      60
      Weighting of End-of-Semester Activities on the Final Grade
      1
      40
      Total

      ECTS / WORKLOAD TABLE

      Semester Activities Number Duration (Hours) Workload
      Theoretical Course Hours
      (Including exam week: 16 x total hours)
      16
      6
      96
      Laboratory / Application Hours
      (Including exam week: '.16.' x total hours)
      16
      0
      Study Hours Out of Class
      5
      4
      20
      Field Work
      0
      Quizzes / Studio Critiques
      0
      Portfolio
      0
      Homework / Assignments
      3
      8
      24
      Presentation / Jury
      0
      Project
      0
      Seminar / Workshop
      0
      Oral Exam
      0
      Midterms
      1
      30
      30
      Final Exam
      1
      40
      40
          Total
      210

       

      COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

      #
      Program Competencies/Outcomes
      * Contribution Level
      1
      2
      3
      4
      5
      1

      Has the fundamental theoretical and practical knowledge, attitudes, and behaviours in nursing and health science for the health and well-being of the individual, family, and public.

      -
      X
      -
      -
      -
      2

      Uses nursing skills with a holistic approach to meet the health care needs of the individual, family, and public.

      -
      -
      X
      -
      -
      3

      Follows evidence-based practices and current approaches while performing nursing practices.

      -
      X
      -
      -
      -
      4

      Follows scientific and technological improvements by adopting the importance of lifelong learning.

      -
      X
      -
      -
      -
      5

      Communicates effectively with individuals, families, communities and healthcare teams in practice setting.

      -
      -
      -
      -
      -
      6

      Makes multidisciplinary teamwork.

      -
      -
      -
      -
      -
      7

      Participates in scientific research, projects, and activities in the field of nursing.

      -
      -
      X
      -
      -
      8

      Uses problem-solving and critical thinking skills in nursing practice.

      -
      -
      -
      -
      -
      9

      Acts in accordance with legal and ethical values in nursing practice.

      -
      X
      -
      -
      -
      10

      Communicate with colleagues, patients, and their relatives using at least one foreign language.

      -
      -
      -
      -
      -

      *1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest


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